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ASK1-IN-2 [2541792-70-3]

Research Use Only
T9377
TargetMol Chemicals
CAS Number2541792-70-3
DownloadMSDS
Product group Chemicals
Molecular Weight364.38
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Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ASK1-IN-2 [2541792-70-3]
  • Delivery Days Customer
    4
  • CAS Number
    2541792-70-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    ASK1-IN-2
  • Molecular Formula
    C19H17FN6O
  • Molecular Weight
    364.38
  • Scientific Description
    ASK1-IN-2 is a potent, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. It has potential therapeutic applications for ulcerative colitis[1].
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)n1cnnc1-c1cccc(NC(=O)c2cc3ccc(F)cc3[nH]2)n1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Hou S, et, al. Structure-based discovery of 1H-indole-2-carboxamide derivatives as potent ASK1 inhibitors for potential treatment of ulcerative colitis. Eur J Med Chem. 2020 Dec 24;211:113114.
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