ASNA1 Polyclonal Antibody

Reddot Biotech

ASNA1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.26 mg/ml

Unconjugated

GET3

guided entry of tail-anchored proteins factor 3, ATPase

arsA arsenite transporter, ATP-binding, homolog 1; ARSA1; ARSA-I; ASNA1; ASNA-I; ATPase GET3; golgi to ER traffic 3 homolog; transmembrane domain recognition complex 40 kDa ATPase subunit; TRC40

Rabbit

IgG

ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.

Human, Mouse

-20°C

12352203