ASPSCR1 Antibody

Cusabio

ASPSCR1 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution. Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J.S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.

Human

-20°C or -80°C

12352203