Bio-Connect

ASR-490

HY-144899
MedChem Express
Estimated Purity99.05
Product group Chemicals
Molecular Weight575.69
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ASR-490
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    99.05
  • Molecular Formula
    C34H41NO7
  • Molecular Weight
    575.69
  • Scientific Description
    ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and Notch1/HCT116 in xenotransplanted mice [1] .
  • SMILES
    C[C@]([C@](CC[C@@]12C)([H])[C@@]([C@]1([H])CC[C@]2([H])[C@@H]([C@@](OC3=O)([H])CC(C)=C3CO)C)([H])C4)(C5=O)[C@@]6([C@H](C=C5)OC(C7=CC=CC=N7)=O)[C@]4([H])O6
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200