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96-Well ROCK Activity Assay Kit

Research Use Only
STA-416
Cell Biolabs
Product group Assays
€ 1.130,00
96 assays
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Overview

  • Supplier
    Cell Biolabs
  • Product Name
    96-Well ROCK Activity Assay Kit
  • Delivery Days Customer
    4
  • Assay Detection Range
    Colorimetric
  • Category Supplier
    Kit
  • Certification
    Research Use Only
  • Scientific Description
    Rho-associated Kinase (ROCK) mediates Rho signaling and reorganizes the actin cytoskeleton by phosphorylation of several substrates that contribute to the assembly of actin filaments and contractility. ROCK inactivates myosin phosphatase through the specific phosphorylation of myosin phosphatase target subunit 1 (MYPT1) at Thr-696, which results in an increase in the phosphorylated content of the 20-kDa myosin light chain (MLC20). Our 96-Well ROCK Activity Assay Kit uses a safe, non-radioactive format to measure the level of active Rho Kinase in cell or tissue lysates. The kit contains a strip-well plate pre-coated with recombinant MYPT1.
  • Storage Instruction
    Store active ROCK-II at -80ºC, ATP Solution at -20ºC and all other kit components at 4ºC. Avoid multiple freeze/thaw cycles.
  • UNSPSC
    41116133