Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC] [1104011-59-7]

South Bay Bio

Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC] [1104011-59-7]

10

Research Use Only

>95%

Ac-WLA-AMC is a fluorogenic peptid substrate for measuring chymotrypsin-like activity of the proteasome. Hydrolysis of this substrate by the beta5-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This substrate is specific to the constitutive proteasome and is not hydrolyzed efficiently by the immunoproteasome. 20S Proteasome enzyme requires activation with 0.035% SDS in the assay buffer. - Chemical. CAS: 1104011-59-7. Formula: C32H37N5O6. MW: 587.7. Synthetic. Ac-WLA-AMC is a fluorogenic peptid substrate for measuring chymotrypsin-like activity of the proteasome. Hydrolysis of this substrate by the beta5-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This substrate is specific to the constitutive proteasome and is not hydrolyzed efficiently by the immunoproteasome. 20S Proteasome enzyme requires activation with 0.035% SDS in the assay buffer.

2°C to 8°C,-20°C

41116133