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ProductsBack/Astaxanthin [472-61-7]
Chemical Structure
Chemical Structure
Chemical Structure

Astaxanthin [472-61-7]

Research Use Only
AG-CN2-0055
AdipoGen Life Sciences
CAS Number472-61-7
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Product group Chemicals
Estimated Purity>98%
Molecular Weight596.8
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Astaxanthin [472-61-7]
  • Delivery Days Customer
    10
  • CAS Number
    472-61-7
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C40H52O4
  • Molecular Weight
    596.8
  • Scientific Description
    Chemical. CAS: 472-61-7. Formula: C40H52O4. MW: 596.8. Synthetic. Potent antioxidant carotenoid. Free radical scavenger. Reduces oxidative stress. Anticancer compound. Anti-inflammatory. Blocks NF-kappaB activation. Anti-hypertensive. Cardiovascular protective. Improves neuronal stem cell potential. Neuroprotective. Inhibits tumor invasion. Apoptosis inducer . Increases insulin sensitivity. Attenuates diabetes associated coagulatory, oxidative and inflammatory stress. PPARalpha agonist and PPARgamma antagonist. Shows positive effects on obesity and insulin resistance Hepatoprotective. Reviews. - Potent antioxidant carotenoid [1]. Free radical scavenger [1, 3]. Reduces oxidative stress [1, 3]. Anticancer compound [2]. Anti-inflammatory. Blocks NF-kappaB activation [3, 18]. Anti-hypertensive. Cardiovascular protective [4, 6]. Improves neuronal stem cell potential [7, 9]. Neuroprotective [10]. Inhibits tumor invasion [11]. Apoptosis inducer [14]. Increases insulin sensitivity [12]. Attenuates diabetes associated coagulatory, oxidative and inflammatory stress [17]. PPARalpha agonist and PPARgamma antagonist [19, 20]. Shows positive effects on obesity and insulin resistance [17, 19, 20] Hepatoprotective [21]. Reviews [5, 6, 15, 16].
  • SMILES
    C\C(\C=C\C=C(/C)\C=C\C1=C(C)C(=O)C(O)CC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C(=O)C(O)CC1(C)C
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Antioxidant activities of astaxanthin and related carotenoids: Y.M. Naguib; J. Agric. Food Chem. 48, 1150 (2000)
  • Antitumor activity of astaxanthin and its mode of action: H. Jyonouchi, et al.; Nutr. Cancer 36, 59 (2000)
  • Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation: S.J. Lee, et al.; Mol. Cells 16, 97 (2003)
  • Antihypertensive potential and mechanism of action of astaxanthin: II. Vascular reactivity and hemorheology in spontaneously hypertensive rats: G. Hussein, et al.; Biol. Pharm. Bull. 28, 967 (2005)
  • Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease: F.J. Pashkow, et al.; Am. J. Cardiol. 101, 58D (2008) (Review)
  • Astaxanthin, oxidative stress, inflammation and cardiovascular disease: R.G. Fassett & J.S. Coombes; Future Cardiol. 5, 333 (2009) (Review)
  • Astaxanthin Improves Stem Cell Potency via an Increase in the Proliferation of Neural Progenitor Cells: J.H. Kim, et al.; Int. J. Mol. Sci. 11, 5109 (2010)
  • Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans: J.S. Park, et al.; Nutr. Metab. (Lond). 7, 18 (2010)
  • Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells: J.H. Kim, et al.; Food Chem. Toxicol. 48, 1741 (2010)
  • Neuroprotective effect of astaxanthin on H(2)O(2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo: Y.P. Lu, et al.; Brain Res. 1360, 40 (2010)