Bio-Connect

Ataxin 1 Antibody: RPE

ORB150782
Biorbyt
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAtxn1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Ataxin 1 antibody
  • Delivery Days Customer
    16
  • Application Supplier Note
    1 microg/ml of SMC-455 was sufficient for detection of Ataxin-1 in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Applications Supplier
    WB (1:1000), ICC/IF (1:100) ICC, IF, IHC, WB
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    N76/8 (Formerly sold as S76-8)
  • Concentration
    1 mg/ml
  • Conjugate
    RPE
  • Gene ID20238
  • Target name
    Atxn1
  • Target description
    ataxin 1
  • Target synonyms
    2900016G23Rik; ataxin-1; Atx; Atx1; C85907; Gm10786; Sc; Sca1; spinocerebellar ataxia 1 homolog
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP54254
  • Protein Name
    Ataxin-1
  • Scientific Description
    Mouse monoclonal to Ataxin 1 (RPE). Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons..
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    See Manual
  • UNSPSC
    12352203