Atecegatran

MedChem Express

Atecegatran

9

Research Use Only

C21H21ClF2N4O4

466.87

Atecegatran (AR-H067637) is an orally active competitive thrombin inhibitor with a K i of 2-4 nM. AR-H067637 inhibits platelet activation and aggregation by blocking thrombin binding to fibrin and thrombomodulin . Atecegatran demonstrates significant anticoagulant effects in various plasma coagulation assays, with an IC 50 ranging from 93 to 220 nM. Atecegatran can be used in research related to thromboembolic disorders [1] .

O=C([C@H](O)C1=CC(OC(F)F)=CC(Cl)=C1)N(CC2)[C@@H]2C(NCC3=CC=C(C=C3)C(N)=N)=O

12352200