ATG12 antibody [GT166]
GTX629815
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, Other Application
Product group Antibodies
ReactivityHuman, Mouse
TargetATG12
Overview
- SupplierGeneTex
- Product NameATG12 antibody [GT166]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT166
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9140
- Target nameATG12
- Target descriptionautophagy related 12
- Target synonymsAPG12; Apg12 (autophagy, yeast) homolog; APG12 autophagy 12-like; APG12L; ATG12 autophagy related 12 homolog; FBR93; HAPG12; ubiquitin-like protein ATG12
- HostMouse
- IsotypeIgG2b
- Protein IDO94817
- Protein NameUbiquitin-like protein ATG12
- Scientific DescriptionAutophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hypoxia Shapes Autophagy in LPS-Activated Dendritic Cells. Monaci S et al., 2020, Front ImmunolRead more
- BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Lin TY et al., 2020 Jul, AutophagyRead more
- Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling. Chang HP et al., 2018 Mar 2, Int J OncolRead more