ATI-2341
HY-P0172
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameATI-2341 [1337878-62-2]
- Delivery Days Customer10
- CertificationResearch Use Only
- Scientific DescriptionATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4) , which functions as a biased ligand, favoring Galphai activation over Galpha13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) [1] [2] .
- UNSPSC12352202