ATI-2341 (TFA)

MedChem Express

ATI-2341 (TFA)

10

Research Use Only

96.71

ATI-2341 is a potent and functionally selective allosteric agonist of C-X-C chemokine receptor type 4 (CXCR4) , which functions as a biased ligand, favoring Galphai activation over Galpha13. ATI-2341 activates the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization. ATI-2341 is a potent and efficacious mobilizer of bone marrow polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) [1] [2] .

-20°C,-80°C

12352202