ATP2B4 Polyclonal Antibody
RD265735A
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetATP2B4
Overview
- SupplierReddot Biotech
- Product NameATP2B4 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID493
- Target nameATP2B4
- Target descriptionATPase plasma membrane Ca2+ transporting 4
- Target synonymsATP2B2; ATPase, Ca++ transporting, plasma membrane 4; matrix-remodeling-associated protein 1; MXRA1; plasma membrane calcium-transporting ATPase 4; PMCA4; PMCA4b; PMCA4x; sarcolemmal calcium pump
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.
- ReactivityMouse
- Storage Instruction-20°C
- UNSPSC12352203