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ATP7B Polyclonal Antibody

Research Use Only
RD83424A
Reddot Biotech
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse
TargetATP7B
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ATP7B Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID540
  • Target name
    ATP7B
  • Target description
    ATPase copper transporting beta
  • Target synonyms
    ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; copper pump 2; copper-transporting ATPase 2; copper-transporting protein ATP7B; PWD; WC1; WD; Wilson disease-associated protein; WND
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203