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ATRX / RAD54 (Alpha Thalassemia Mental Retardation)(23c), CF640R conjugate, 0.1mg/mL [26628-22-8]

ATRX / RAD54 (Alpha Thalassemia Mental Retardation)(23c), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401474
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetATRX
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Overview

  • Supplier
    Biotium
  • Product Name
    ATRX / RAD54 (Alpha Thalassemia Mental Retardation)(23c), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    23c
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID546
  • Target name
    ATRX
  • Target description
    ATRX chromatin remodeler
  • Target synonyms
    alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); ATP-dependent helicase ATRX; JMS; MRX52; RAD54; RAD54L; transcriptional regulator ATRX; XH2; X-linked helicase II; X-linked nuclear protein; XNP; ZNF-HX
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP46100
  • Protein Name
    Transcriptional regulator ATRX
  • Scientific Description
    ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203