Atuveciclib (BAY-1143572)

Selleck Chemicals

Atuveciclib (BAY-1143572) [1414943-88-6]

9

Research Use Only

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Atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with IC50 values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3alpha and GSK3beta respectively.

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