ATXN3 antibody, PAb
ORB180467
ApplicationsWestern Blot
Product group Antibodies
ReactivityAll Species, Chicken, Equine, Feline, Hamster, Human, Mouse, Rabbit, Rat, Sheep
Overview
- SupplierBiorbyt
- Product NameATXN3 antibody, PAb
- Delivery Days Customer10
- ApplicationsWestern Blot
- Applications SupplierWB: 1:250-1:2000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- HostGoat
- IsotypeIgG
- Scientific DescriptionGoat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
- ReactivityAll Species, Chicken, Equine, Feline, Hamster, Human, Mouse, Rabbit, Rat, Sheep
- UNSPSC12352203