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Avacincaptad pegol sodium

Research Use Only
HY-147080
MedChem Express
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Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Avacincaptad pegol sodium
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.53
  • Molecular Formula
    C395H453F21N142Na39O262P39 (C2H4O)2n
  • Molecular Weight
    53500 (Approximately)
  • Scientific Description
    Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy (GA) mice[1][2][3][4].
  • SMILES
    [Avacincaptad pegol sodium]
  • Storage Instruction
    -20°C
  • UNSPSC
    41106300