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Avadomide (hydrochloride)

HY-100507A
MedChem Express
Molecular Weight322.75
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Avadomide (hydrochloride)
  • Delivery Days Customer
    5
  • Molecular Formula
    C14H15ClN4O3
  • Molecular Weight
    322.75
  • Scientific Description
    Avadomide hydrochloride (CC 122 hydrochloride) is the hydrochloride form of Avadomide (HY-100507). Avadomide hydrochloride is an orally active cereblon modulator. Avadomide hydrochloride modulates cereblon E3 ligase activity, inhibits NF-kappaB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide hydrochloride exhibits potent antitumor and immunomodulatory activities [1] [2] [3] .
  • SMILES
    O=C(N1)C(CCC1=O)N2C(C)=NC3=C(C2=O)C(N)=CC=C3.[H]Cl
  • UNSPSC
    12352200