Avadomide (hydrochloride)
HY-100507A
Overview
- SupplierMedChem Express
- Product NameAvadomide (hydrochloride)
- Delivery Days Customer5
- Molecular FormulaC14H15ClN4O3
- Molecular Weight322.75
- Scientific DescriptionAvadomide hydrochloride (CC 122 hydrochloride) is the hydrochloride form of Avadomide (HY-100507). Avadomide hydrochloride is an orally active cereblon modulator. Avadomide hydrochloride modulates cereblon E3 ligase activity, inhibits NF-kappaB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide hydrochloride exhibits potent antitumor and immunomodulatory activities [1] [2] [3] .
- SMILESO=C(N1)C(CCC1=O)N2C(C)=NC3=C(C2=O)C(N)=CC=C3.[H]Cl
- UNSPSC12352200