Avitinib (AC0010) [1557267-42-1]
S8741
CAS Number1557267-42-1
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameAvitinib (AC0010) [1557267-42-1]
- Delivery Days Customer9
- CAS Number1557267-42-1
- CertificationResearch Use Only
- Scientific DescriptionAvitinib (AC0010) is a pyrrolopyrimidine-based irreversible EGFR inhibitor that is mutation-selective with IC50 value of 0.18 nM against EGFR L858R/T790M double mutations, nearly 43-fold greater potency over wild-type EGFR (IC50 value, 7.68 nM). It has comparable anti-tumor activity and tolerated toxicity.
- UNSPSC12352200