AY 254 [2093408-03-6]

TargetMol Chemicals

AY 254 [2093408-03-6]

999

Chemical

Research Use Only

AY 254

C30H49N9O6

631.779

AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro.

3 years

C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C1CCCCC1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O - @@:25 -

-20°C

12352200