AZ-4217 [1383846-83-0]

TargetMol Chemicals

AZ-4217 [1383846-83-0]

72

Chemical

Research Use Only

AZ-4217

C30H25FN4O

476.54

AZ-4217 is a high potency BACE inhibitor. It displays acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy.

3 years

NC1=N[C@](C=2C1=C(F)C=CC2)(C3=CN(CC)C(=O)C(C)=C3)C4=CC(=CC=C4)C=5C=C(C#CC)C=NC5

-20°C

12352200