AZ1495
HY-111101
CAS Number2196204-23-4
Product group Chemicals
Estimated Purity98.07
Molecular Weight385.50
Overview
- SupplierMedChem Express
- Product NameAZ1495 [2196204-23-4]
- Delivery Days Customer10
- CAS Number2196204-23-4
- CertificationResearch Use Only
- Estimated Purity98.07
- Molecular FormulaC21H31N5O2
- Molecular Weight385.50
- Scientific DescriptionAZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC 50 values of 0.005 microM and 0.023 microM, respectively. AZ1495 has IRAK4 inhibition with a K d value of 0.0007 microM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL) [1] .
- SMILESC1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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Estimated Purity98.36%
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