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AZ1495

HY-111101
MedChem Express
CAS Number2196204-23-4
DownloadMSDS
Product group Chemicals
Estimated Purity98.07
Molecular Weight385.50
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AZ1495 [2196204-23-4]
  • Delivery Days Customer
    10
  • CAS Number
    2196204-23-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.07
  • Molecular Formula
    C21H31N5O2
  • Molecular Weight
    385.50
  • Scientific Description
    AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC 50 values of 0.005 microM and 0.023 microM, respectively. AZ1495 has IRAK4 inhibition with a K d value of 0.0007 microM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL) [1] .
  • SMILES
    C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200