AZ194

MedChem Express

AZ194 [2241651-99-8]

10

2241651-99-8

Research Use Only

99.83

C34H31F2N3O3

567.63

AZ194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 ( IC 50 =1.2 microM). AZ194 blocks SUMOylation of CRMP2 to selectively reduce the amount of surface-expressed NaV1.7. Antinociceptive effects [1] .

O=C(N1CCC(CC1)C2=NC3=C(N2CC4=CC(F)=CC=C4)C=CC=C3)C5=CC=C(C(OC)=C5)OCC6=CC(F)=CC=C6

-20°C,2°C to 8°C

12352200