AZ304 [942507-42-8]

Biorbyt

AZ304 [942507-42-8]

16

942507-42-8

Research Use Only

C27H25N5O2

451.5197

AZ304 is a novel potent, dual BRAF inhibitor targeting the kinase domains of wild type BRAF, V600E mutant BRAF and wild type CRAF with IC50 of 79 nM, 38 nM and 68 nM, respectively.

O=C(C1C([H])=C([H])C([H])=C(C=1[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])N([H])C1C([H])=C([H])C(C([H])([H])[H])=C(C=1[H])N([H])C1C2C([H])=C([H])C(=C([H])C=2N=C([H])N=1)OC([H])([H])[H]

12352200