AZD-4877 [758722-49-5]

TargetMol Chemicals

AZD-4877 [758722-49-5]

9

Chemical

Research Use Only

AZD-4877

99.87%

C28H33N5O2S

503.66

AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC).

3 years

C(N(C(=O)C1=CC=C(C)C=C1)CCCN)(C(C)C)C=2N(CC3=CC=CC=C3)C(=O)C4=C(N2)SN=C4C

-20°C

12352200