AZD-6918 [905585-60-6]

TargetMol Chemicals

AZD-6918 [905585-60-6]

72

Chemical

AZD-6918

C20H20F2N6O

398.41

AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth.

3 years

N([C@@H](C)C1=CC=C(F)C=C1)C2=C(C#N)C=C(F)C(NC=3C=C(OC(C)C)NN3)=N2

-20°C

12352200