Palacaparib

MedChem Express

AZD-9574

10

Research Use Only

99.11

C21H22F2N6O2

428.44

AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD + ?breast cancer and advanced solid malignancies research [1] .

O=C(C1=NC(F)=C(N2CCN(CC2)CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)C=C1)NC

-20°C,2°C to 8°C

12352200