AZD8421
E1972
Estimated Purity...
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameAZD8421
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionAZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2), with an IC50 against CDK2 of 9nM with selectivity over CDK1, CDK4 and CDK6. It also exhibits an anti-proliferative effect, effectively inhibits Rb phosphorylation, and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models.
- UNSPSC51202000