Azepexole (hydrochloride)

MedChem Express

Azepexole (hydrochloride)

5

Research Use Only

C9H16ClN3O

217.70

Azepexole hydrochloride (B-HT 933 dihydrochloride; Oxazoloazepin dihydrochloride) is a selective agonist for alpha 2-adrenoceptor , with pK i of 8.3, 7.6, and 7.5 for alpha2A-, alpha2B- and alpha2C-adrenoceptor subtypes, resepctively. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions with IC 50 of 78.72 nM. Azepexole hydrochloride exhibits antitussive and analgesic efficacy [1] [2] .

CCN(CC1)CCC2=C1OC(N)=N2.Cl

12352200