Azvudine (hydrochloride)

MedChem Express

Azvudine (hydrochloride) [1333126-31-0]

9

1333126-31-0

Research Use Only

95.23

C9H12ClFN6O4

322.68

Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV , HBV and HCV . Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC 50 s ranging from 0.03 to 6.92 nM) and HIV-2 (EC 50 s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains [1] . Azvudine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C(N=C(N)C=C2)=O)[C@H]1F.Cl

2°C to 8°C

12352200