b-AP15 (NSC-687852) [1009817-63-3]
27701
CAS Number1009817-63-3
Product group Chemicals
Estimated Purity≥98%
Molecular Weight419.4 Da
Overview
- SupplierBPS Bioscience
- Product Nameb-AP15 (NSC-687852) [1009817-63-3]
- Delivery Days Customer7
- CAS Number1009817-63-3
- CertificationResearch Use Only
- Estimated Purity≥98%
- Molecular FormulaC22H17N3O6
- Molecular Weight419.4 Da
- Scientific DescriptionBlocks 26S proteasome activity by inhibiting the ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) activities of the 19S regulatory subunit without affecting the catalytic activity of the 20S core subunit. b-AP15 displays several differences to bortezomib including insensitivity to over-expression of the anti-apoptotic mediator Bcl-2 and anti-tumor activity in four solid tumor models.
- UNSPSC12352200