B3GALNT1 Polyclonal Antibody
RD84691A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetB3GALNT1
Overview
- SupplierReddot Biotech
- Product NameB3GALNT1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8706
- Target nameB3GALNT1
- Target descriptionbeta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- Target synonymsB3GALT3; b3Gal-T3; beta-1,3-galactosyltransferase 3; beta-1,3-GalNAc-T1; beta-1,3-GalTase 3; beta3Gal-T3; beta-3-Gx-T3; brainiac1; galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; galT3; Gb4Cer; GLCT3; GLOB; globoside synthase; globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase; P; P antigen synthase; P blood group globoside; P1; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 (Globoside blood group); UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 1 (Globoside blood group); UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203