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B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

TMPK-00314
TargetMol Chemicals
Molecular Weight49.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    49.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
  • Scientific Description
    B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig-B7-H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.5 kDa and the accession number is Q5ZPR3-1.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200