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B7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL [26628-22-8]

B7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC041788
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetVTCN1
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Overview

  • Supplier
    Biotium
  • Product Name
    B7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B7H4/1788
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID79679
  • Target name
    VTCN1
  • Target description
    V-set domain containing T cell activation inhibitor 1
  • Target synonyms
    B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7S1; B7X; immune costimulatory protein B7-H4; PRO1291; T cell costimulatory molecule B7x; VCTN1; V-set domain-containing T-cell activation inhibitor 1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDQ7Z7D3
  • Protein Name
    V-set domain-containing T-cell activation inhibitor 1
  • Scientific Description
    B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203