![B7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL [26628-22-8] B7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-244.jpeg)
B7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC041788
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetVTCN1
Overview
- SupplierBiotium
- Product NameB7-H4 (Immuno-Inhibitory Protein)(B7H4/1788), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB7H4/1788
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID79679
- Target nameVTCN1
- Target descriptionV-set domain containing T cell activation inhibitor 1
- Target synonymsB7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7S1; B7X; immune costimulatory protein B7-H4; PRO1291; T cell costimulatory molecule B7x; VCTN1; V-set domain-containing T-cell activation inhibitor 1
- HostMouse
- IsotypeIgG2a
- Protein IDQ7Z7D3
- Protein NameV-set domain-containing T-cell activation inhibitor 1
- Scientific DescriptionB7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203