BAG2 Protein, Human, Recombinant (His)

TargetMol Chemicals

BAG2 Protein, Human, Recombinant (His)

16

Research Use Only

SDS-PAGE: 95.19%; SEC-HPLC: 97.85%

25-30 KDa (reducing condition)

BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

-20°C

12352200