BAK1 Polyclonal Antibody
RD79971A
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBAK1
Overview
- SupplierReddot Biotech
- Product NameBAK1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID578
- Target nameBAK1
- Target descriptionBCL2 antagonist/killer 1
- Target synonymsapoptosis regulator BAK; BAK; BAK-LIKE; bcl-2 homologous antagonist/killer; BCL2L7; bcl2-L-7; BCL2-like 7 protein; bcl-2-like protein 7; CDN1; pro-apoptotic protein BAK
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203