Banoxantrone [136470-65-0]

TargetMol Chemicals

Banoxantrone [136470-65-0]

72

Chemical

Research Use Only

Banoxantrone

C22H28N4O6

444.48

Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. This compound demonstrates significant cytotoxicity with its hypoxia-selective action being augmented by radiation.

3 years

N(CCN(C)(C)=O)C1=C2C(=C(NCCN(C)(C)=O)C=C1)C(=O)C=3C(C2=O)=C(O)C=CC3O

-20°C

12352200