Barasertib (dihydrochloride)

MedChem Express

Barasertib (dihydrochloride)

5

C26H33Cl2FN7O6P

660.46

Barasertib (AZD1152 dihydrochloride), a pro-drug of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC 50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152 dihydrochloride) induces growth arrest and apoptosis in cancer cells [1] .

O=C(CC1=NNC(NC2=C3C=CC(OCCCN(CCOP(O)(O)=O)CC)=CC3=NC=N2)=C1)NC4=CC(F)=CC=C4.Cl.Cl

12352200