BARD1 antibody
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ORB67159
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetBARD1
Overview
- SupplierBiorbyt
- Product NameBARD1 antibody
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:500-1:1000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID580
- Target nameBARD1
- Target descriptionBRCA1 associated RING domain 1
- Target synonymsBRCA1-associated RING domain gene 1; BRCA1-associated RING domain protein 1; RING-type E3 ubiquitin transferase BARD1
- HostRabbit
- Protein IDQ99728
- Protein NameBRCA1-associated RING domain protein 1
- Scientific DescriptionRabbit polyclonal to BARD1.BRCA1-associated RING domain protein 1 (BARD1) is a probable E3 ubiquitin-protein ligase and atumor suppressor. The BRCA1-BARD1 heterodimer specifically mediates the formation of Lys-6-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNAdamage repair, ubiquitination and transcriptional regulation to maintain genomic stability. BARD1plays a central role in the control of the cell cycle in response to DNA damage. It also forms aheterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibitingpre-mRNA 3 cleavage.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203