Bio-Connect

BARD1 antibody

Research Use Only
ORB67159
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetBARD1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    BARD1 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:500-1:1000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID580
  • Target name
    BARD1
  • Target description
    BRCA1 associated RING domain 1
  • Target synonyms
    BRCA1-associated RING domain gene 1; BRCA1-associated RING domain protein 1; RING-type E3 ubiquitin transferase BARD1
  • Host
    Rabbit
  • Protein IDQ99728
  • Protein Name
    BRCA1-associated RING domain protein 1
  • Scientific Description
    Rabbit polyclonal to BARD1.BRCA1-associated RING domain protein 1 (BARD1) is a probable E3 ubiquitin-protein ligase and atumor suppressor. The BRCA1-BARD1 heterodimer specifically mediates the formation of Lys-6-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNAdamage repair, ubiquitination and transcriptional regulation to maintain genomic stability. BARD1plays a central role in the control of the cell cycle in response to DNA damage. It also forms aheterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibitingpre-mRNA 3 cleavage.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203