Baricitinib (INCB28050, LY3009104)

Biorbyt

Baricitinib (INCB28050, LY3009104) [1187594-09-7]

16

1187594-09-7

Research Use Only

C16H17N7O2S

371.41688

Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2,showed potent activity against COVID-19(SARS-COV-2).

N(S(CC)(=O)=O)1CC(N2C=C(C3N=CN=C4NC=CC4=3)C=N2)(CC#N)C1

12352200