Western blot analysis of extracts from HepG2 cells, using Bax (Ab-167) antibody.
BAX (Ab-167) Antibody
CSB-PA834415
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetBAX
Overview
- SupplierCusabio
- Product NameBAX (Ab-167) Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID581
- Target nameBAX
- Target descriptionBCL2 associated X, apoptosis regulator
- Target synonymsapoptosis regulator BAX; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2-associated X protein omega; BCL2L4; bcl2-L-4; bcl-2-like protein 4
- HostRabbit
- IsotypeIgG
- Protein IDQ07812
- Protein NameApoptosis regulator BAX
- Scientific DescriptionAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. Oltvai Z.N., Cell 74:609-619(1993). Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001). Guo B., Nature 423:456-461(2003)
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203