Western blot analysis of extracts from 293 cells, using Bax antibody.
BAX Antibody
CSB-PA167247
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetBAX
Overview
- SupplierCusabio
- Product NameBAX Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID581
- Target nameBAX
- Target descriptionBCL2 associated X, apoptosis regulator
- Target synonymsapoptosis regulator BAX; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2-associated X protein omega; BCL2L4; bcl2-L-4; bcl-2-like protein 4
- HostRabbit
- IsotypeIgG
- Protein IDQ07812
- Protein NameApoptosis regulator BAX
- Scientific DescriptionAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. Francesca Andriani, J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324. H Martinez-Valdez, J. Exp. Med., Mar 1996; 183: 971. Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312. Renren Wen, Mol. Cell. Biol., Jan 2001; 21: 678 - 689.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203