Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using BAX antibody.
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using BAX antibody.
BAX Antibody
CSB-PA552355
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetBAX
Overview
- SupplierCusabio
- Product NameBAX Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID581
- Target nameBAX
- Target descriptionBCL2 associated X, apoptosis regulator
- Target synonymsapoptosis regulator BAX; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2-associated X protein omega; BCL2L4; bcl2-L-4; bcl-2-like protein 4
- HostRabbit
- IsotypeIgG
- Protein IDP55269
- Protein NameApoptosis regulator BAX
- Scientific DescriptionThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. Apte S.S., Genomics 26:592-594(1995). Guo B., Nature 423:456-461(2003).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203