BAY-985

Selleck Chemicals

BAY-985

9

Research Use Only

BAY-985 is a potent and highly selective TBK1/IKKepsilon inhibitor. BAY-985 shows high potency toward TBK1 (IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKepsilon(IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM).

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