BBC3 Polyclonal Antibody

Reddot Biotech

BBC3 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot

Research Use Only

1 mg/ml

Unconjugated

BBC3

BCL2 binding component 3

bcl-2-binding component 3; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; p53-upregulated modulator of apoptosis; PUMA

Rabbit

IgG

This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Human, Mouse, Rat

-20°C

12352203