Bcl-2-IN-7

TargetMol Chemicals

Bcl-2-IN-7

114

Chemical

Research Use Only

Bcl-2-IN-7

C24H22N4O5S2

510.59

Bcl-2-IN-7 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2), which can downregulate the expression of Bcl-2, increase the expression of p53, Bax, caspase-7 mRNA, and induce cell cycle arrest and apoptosis in MCF-7 cells of breast cancer. Bcl2-IN-7 showed good antitumor activity against MCF-7 cells (IC50: 20.17 microM), LoVo cells (IC50: 22.64 microM), HepG2 cells (IC50: 45.57 microM) and A549 cells (IC50: 51.50 microM).

3 years

-20°C

51202000