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Western Blot analysis of 293T cells using Bcl-x Polyclonal Antibody at dilution of 1:500.
Western Blot analysis of 293T cells using Bcl-x Polyclonal Antibody at dilution of 1:500.
Western Blot analysis of 293T cells using Bcl-x Polyclonal Antibody at dilution of 1:500.

Bcl-x Polyclonal Antibody

Research Use Only
E-AB-30640
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    Bcl-x Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    WB,IHC,IF,ELISA
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Scientific Description
    Bcl x is a member of the Bcl 2 family of proteins, which function as regulators of apoptosis. It may provide neuroprotection against ischemic brian injury. Bcl x has two isoforms, Bcl xl (long) a 241 amino acid protein and Bcl xs (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl2 family. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
  • UNSPSC
    12352203