BCL-xL/BCL-2 ligand 1

MedChem Express

BCL-xL/BCL-2 ligand 1

5

Research Use Only

C48H53ClF3N5O7S3

1000.61

BCL-xL/BCL-2 ligand 1 (compound 72-1) is a BCL-xL and BCL-2 protein ligand. BCL-xL/BCL-2 ligand 1 can be connected to the E3 ligase by a linker to form PROTACs (HY-161410)[1][2].

O=C[C@@](C)(C1)CCC(C2=CC=C(C=C2)Cl)=C1CN3CCN(C4=CC=C(C=C4)C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(C=C5)N[C@@H](CSC6=CC=CC=C6)CCN7[C@]8([H])C[C@](OC8)([H])C7)=O)=O)CC3

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