BCL10 peptide

GeneTex

BCL10 peptide

7

The peptide is used for blocking the activity of BcL10 (GTX28398)Incubatingthe peptide with equal volume of antibody for 30 min at 37C usually completely blocks theantibody activity in Western blotting.

Neutralisation/Blocking

Research Use Only

0.20 mg/ml

Unconjugated

Bcl10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl 10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl10 cellular overexpression induces JNK, p38, and NF-kappaB activation. Deregulation of Bcl10 expression was also demonstrated to be involved in cellular oncogenesis.

-20°C

12352202